Quotation from: Manual of Surgery

Written by: Alexander Miles and Alexis Thomson


#Tuberculous Osteomyelitis.#--Tuberculous lesions in the marrow occur as
isolated or as multiple foci of granulation tissue, which replace the
marrow and erode the trabeculae of bone in the vicinity (Fig. 124). The
individual focus varies in size from a pea to a walnut. The changes that
ensue resemble in character those in other tissues, and the extent of
the destruction varies according to the way in which the tubercle
bacillus and the marrow interact upon one another. The granulation
tissue may undergo caseation and liquefaction, or may become
encapsulated by fibrous tissue--"encysted tubercle."

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