Quotation from: Manual of Surgery

Written by: Alexander Miles and Alexis Thomson


_Differential Diagnosis._--Acute osteomyelitis is to be diagnosed from
infections of the soft parts, such as erysipelas and cellulitis, and, in
the case of the tibia, from erythema nodosum. Tenderness localised to
the ossifying junction is the most valuable diagnostic sign of
osteomyelitis.


When there is early and pronounced general intoxication, there is likely
to be confusion with other acute febrile illnesses, such as scarlet
fever. In all febrile conditions in children and adolescents, the
ossifying junctions of the long bones should be examined for areas of
pain and tenderness.

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