Quotation from: Manual of Surgery

Written by: Alexander Miles and Alexis Thomson


While the occurrence of purely periosteal suppuration is regarded as
possible, we are of opinion that the embolic form of staphylococcal
osteomyelitis always originates in the marrow.


The portion of the diaphysis which has sustained the action of the
concentrated toxins has its vitality further impaired as a result of the
stripping of the periosteum and thrombosis of the blood vessels of the
marrow, so that _necrosis_ of bone is one of the most striking results
of the disease, and as this takes place rapidly, that is, in a day or
two, the term _acute necrosis_, formerly applied to the disease, was
amply justified.

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