Quotation from: Manual of Surgery

Written by: Alexander Miles and Alexis Thomson


The term _rarefying ostitis_ is applied to any process that is attended
with excessive absorption of the framework of a bone, whereby it becomes
more porous or spongy than it was before, a condition known as
_osteoporosis_.


The term _caries_ is employed to indicate any diseased process
associated with crumbling away of the trabecular framework of a bone. It
may be considered as the equivalent of ulceration or molecular
destruction in the soft parts. The carious process is preceded by the
formation of granulation tissue in the marrow or periosteum, which eats
away and replaces the bone in contact with it. The subsequent
degeneration and death of the granulation tissue under the necrotic
influence of bacterial toxins results in disintegration and crumbling
away of the trabecular framework of the portion of bone affected.
Clinically, carious bone yields a soft grating sensation under the
pressure of the probe. The macerated bone presents a rough, eroded
surface.

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