Quotation from: Manual of Surgery

Written by: Alexander Miles and Alexis Thomson


On the other hand, the formation of new bone may be _exaggerated_, the
osteoblasts being excited to abnormal activity by stimuli of different
kinds: for example, the secretion of certain glandular organs, such as
the pituitary and thyreoid; the diluted toxins of certain
micro-organisms, such as the staphylococcus aureus and the spirochaete of
syphilis; a condition of hyperaemia, such as that produced artificially
by the application of a Bier's bandage or that which accompanies a
chronic leg-ulcer.

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