The clinical features vary a good deal in different cases; the affection
is often obstinate, and may last for many weeks or even months.
In the sciatica that results from neuritis and perineuritis, there is
marked tenderness on pressure due to the involvement of the nerve
filaments in the sheath of the nerve, and there may be patches of
cutaneous anaesthesia, loss of tendon reflexes, localised wasting of
muscles, and vaso-motor and trophic changes. The presence of the
reaction of degeneration confirms the diagnosis of neuritis. In
long-standing cases the pain and discomfort may lead to a postural
scoliosis (_ischias-scoliotica_).
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