Quotation from: Manual of SurgeryWritten by: Alexander Miles and Alexis Thomson |
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The embedded foreign body at first acts as an irritant, and induces a reaction in the tissues in which it lodges, in the form of hyperaemia, local leucocytosis, proliferation of fibroblasts, and the formation of granulation tissue. The subsequent changes depend upon whether or not the wound is infected with pyogenic bacteria. If it is so infected, suppuration ensues, a sinus forms, and persists until the foreign body is either cast out or removed.
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