Occasionally a syphilitic child suffers from a succession of these
gummatous lesions with resulting ill-health, and, it may be, waxy
disease of the internal organs; on the other hand, it may recover and
present no further manifestations of the inherited taint.
_Affections of the Eyes._--At or near puberty there is frequently
observed an affection of the eyes, known as _chronic interstitial
keratitis_, the relationship of which to inherited syphilis was first
established by Hutchinson. It occurs between the ages of six and sixteen
years, and usually affects one eye before the other. It commences as a
diffuse haziness or steaminess near the centre of the cornea, and as it
spreads the entire cornea assumes the appearance of ground glass. The
chief complaint is of dimness of sight, which may almost amount to
blindness, but there is little pain or photophobia; a certain amount of
conjunctival and ciliary congestion is usually present, and there may be
_iritis_ in addition. The cornea, or parts of it, may become of a deep
pink or salmon colour from the formation in it of new blood vessels. The
affection may last for from eighteen months to two years. Complete
recovery usually takes place, but slight opacities, especially in the
site of former salmon patches, may persist, and the disease occasionally
relapses. _Choroiditis_ and _retinitis_ may also occur, and leave
permanent changes easily recognised on examination with the
ophthalmoscope.
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