Quotation from: Manual of Surgery

Written by: Alexander Miles and Alexis Thomson


#Tertiary Syphilis.#--While the manifestations of primary and secondary
syphilis are common, those of the tertiary period are by comparison
rare, and are observed chiefly in those who have either neglected
treatment or who have had their powers of resistance lowered by
privation, by alcoholic indulgence, or by tropical disease.


It is to be borne in mind that in a certain proportion of men and in a
larger proportion of women, the patient has no knowledge of having
suffered from syphilis. Certain slight but important signs may give the
clue in a number of cases, such as irregularity of the pupils or failure
to react to light, abnormality of the reflexes, and the discovery of
patches of leucoplakia on the tongue, cheek, or palate.

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