These preparations are the most efficient therapeutic agents that have
yet been employed in the treatment of syphilis.
The manifestations of the disease disappear with remarkable rapidity.
Observations show that the spirochaetes lose their capacity for movement
within an hour or two of the administration, and usually disappear
altogether in from twenty-four to thirty-six hours. Wassermann's
reaction usually yields a negative result in from three weeks to two
months, but later may again become positive. Subsequent doses of the
arsenical preparation are therefore usually indicated, and should be
given in from 7 to 21 days according to the dose.
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