Quotation from: Manual of Surgery

Written by: Alexander Miles and Alexis Thomson


Syphilis is also to be diagnosed from _epithelioma_, the common form of
cancer of the penis. It is especially in elderly patients with a tight
prepuce that the induration of syphilis is liable to be mistaken for
that associated with epithelioma. In difficult cases the prepuce must be
slit open.


Difficulty may occur in the diagnosis of primary syphilis from _herpes_,
as this may appear as late as ten days after connection; it commences as
a group of vesicles which soon burst and leave shallow ulcers with a
yellow floor; these disappear quickly on the use of an antiseptic
dusting powder.

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