Quotation from: Manual of Surgery

Written by: Alexander Miles and Alexis Thomson


_Extra-genital or Erratic Chancres_ (Fig. 38).--Erratic chancre is the
term applied by Jonathan Hutchinson to the primary lesion of syphilis
when it appears on parts of the body other than the genitals. It differs
in some respects from the hard chancre as met with on the penis; it is
usually larger, the induration is more diffused, and the enlarged glands
are softer and more sensitive. The glands in nearest relation to the
sore are those first affected, for example, the epitrochlear or axillary
glands in chancre of the finger; the submaxillary glands in chancre of
the lip or mouth; or the pre-auricular gland in chancre of the eyelid or
forehead. In consequence of their divergence from the typical chancre,
and of their being often met with in persons who, from age,
surroundings, or moral character, are unlikely subjects of venereal
disease, the true nature of erratic chancres is often overlooked until
the persistence of the lesion, its want of resemblance to anything else,
or the onset of constitutional symptoms, determines the diagnosis of
syphilis. A solitary, indolent sore occurring on the lip, eyelid,
finger, or nipple, which does not heal but tends to increase in size,
and is associated with induration and enlargement of the adjacent
glands, is most likely to be the primary lesion of syphilis.

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