Quotation from: Manual of Surgery

Written by: Alexander Miles and Alexis Thomson


The irritation caused by infection with bacteria, on the other hand, is
cumulative, as the organisms not only multiply in the tissues, but in
addition produce chemical poisons (toxins) which aggravate the
irritative effects. The resulting reaction is correspondingly
progressive, and has as its primary object the expulsion of the irritant
and the limitation of its action. If the natural protective effort is
successful, the resulting tissue changes subserve the process of repair,
but if the bacteria gain the upper hand in the struggle, the
inflammatory reaction becomes more intense, certain of the tissue
elements succumb, and the process for the time being is a destructive
one. During the stage of bacterial inflammation, reparative processes
are in abeyance, and it is only after the inflammation has been allayed,
either by natural means or by the aid of the surgeon, that repair takes
place.

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