Quotation from: Manual of Surgery

Written by: Alexander Miles and Alexis Thomson


_The Iodine or Glycogen Reaction._--The leucocyte count may be
supplemented by staining films of the blood with a watery solution of
iodine and potassium iodide. In all advancing purulent conditions, in
septic poisonings, in pneumonia, and in cancerous growths associated
with ulceration, a certain number of the polynuclear leucocytes are
stained a brown or reddish-brown colour, due to the action of the iodine
on some substance in the cells of the nature of glycogen. This reaction
is absent in serous effusions, in unmixed tuberculous infections, in
uncomplicated typhoid fever, and in the early stages of cancerous
growths.

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